Friday, September 30, 2016

Heart disease exercise program could work for bowel cancer patients

Could rehabilitation programs for heart disease patients be used to help people recovering from bowel cancer get back on their feet? That's the question cancer care experts at the University of Stirling have been exploring.
Researchers have found health and exercise sessions currently provided to individuals recovering from heart disease could also help people who have undergone bowel cancer surgery.
The NHS already uses physical activity to help thousands of people with heart problems improve their chances of survival and quality of life, and Stirling scientists now believe it could be rolled out to help people with an entirely different illness.
Dr Gill Hubbard, Reader in Cancer Care in the Faculty of Health Sciences and Sport, said: "People recovering from bowel cancer surgery are not currently meeting the recommended levels of physical activity after they undergo surgery. This could be for a number of reasons, but often patients do not know if they are safe to exercise.
"We wanted to bring together people recovering from heart disease and bowel cancer to see if the same rehabilitation program could work for both groups. We referred patients with bowel cancer to the cardiac rehabilitation classes and found cardiac patients welcomed those with cancer into their classes. Both groups enjoyed exercising together and supported each other to make a full recovery."
The rehabilitation program involves aerobic and body strengthening exercises for about an hour each week for 12 weeks. Evidence clearly shows that these exercises are good for people with heart disease and cancer, and although cardiac rehabilitation exists for people recovering from a heart attack, there is currently no equivalent rehabilitation program for patients with cancer.
The study, funded by the National Institute for Health Research (NIHR), asked patients to record their physical fitness, quality of life, anxiety, depression and figure before and after the 12-week program and gathered the views of doctors involved in cardiac rehabilitation.
Dr Hubbard continued: "We found cardiac clinicians were happy to involve cancer patients in their programs, but to make this work on a much larger scale additional training would be required to fully support cancer survivors. Although a novel idea, we believe marrying these two quite separate groups during the rehabilitation process could vastly improve the quality of life for lots of people who are recovering from bowel cancer but do not have the confidence to exercise."

Story Source:
Materials provided by University of StirlingNote: Content may be edited for style and length.

Journal Reference:
  1. Gill Hubbard, Julie Munro, Ronan O’Carroll, Nanette Mutrie, Lisa Kidd, Sally Haw, Richard Adams, Angus JM Watson, Stephen J Leslie, Petra Rauchhaus, Anna Campbell, Helen Mason, Sarkis Manoukian, Gillian Sweetman, Shaun Treweek. The use of cardiac rehabilitation services to aid the recovery of patients with bowel cancer: a pilot randomised controlled trial with embedded feasibility studyHealth Services and Delivery Research, 2016; 4 (24): 1 DOI: 10.3310/hsdr04240

Childhood muscular fitness and adult metabolic syndrome

About 20-25 percent of adults have the metabolic syndrome and have increased risk of developing both cardiovascular disease and type 2 diabetes.
In this longitudinal study, investigators examined associations between childhood muscular fitness (strength, endurance, and power) and metabolic syndrome -- the latter assessed once they reached adulthood.
The results suggest that higher levels of childhood muscular fitness might protect against developing metabolic syndrome in adult years. Further, this relationship was found to be independent of the childhood cardiorespiratory fitness levels.
For example, those with the highest muscular fitness at ages 9-15 years, had an 80 percent lower risk of developing metabolic syndrome in adulthood -- in comparison to those who had low muscular fitness levels during childhood.
Supporting the current World Health Organization physical activity guidelines, these results highlight the importance of both muscular strengthening activities and aerobic exercise.
Overall, the study supports that a combination of increased muscular fitness, increased cardiorespiratory fitness and decreased adiposity in childhood may reduce future risk metabolic syndrome.

Story Source:
Materials provided by American College of Sports Medicine (ACSM)Note: Content may be edited for style and length.

Journal Reference:
  1. Constan G. Magnussen et al. Childhood Muscular Fitness Phenotypes and Adult Metabolic SyndromeMedicine & Science in Sports & Exercise, 2016; 48 (9): 1715 DOI:10.1249/MSS.0000000000000955

Moderate to high aerobic capacity decrease the risk of suffering a sudden death event, study suggests

UCA researchers, collaborating with the Exercise and Epidemiology Science and Biostatistics Departments from the University of South Carolina in Columbine (USA), have carried out a study focused in knowing how important the aerobic capacity in the sudden death prevention is, paying special attention to those people who have some pathology such as obesity and hypertension.
This investigation has been leaded by David Jiménez Pavón (Ramón y Cajal researcher) and Vanesa España Romero as a co-author, belonging both to the University of Cadiz. The study has been published in the Mayo Clinic Proceedings (from the Fundación de Investigación Mayo) and has had as reference the "Aerobics Center Longitudinal Study-ACLS" project.
To carry on with this study, more than 55,000 people from the USA were evaluated and were followed up during an average of 14 years. All of them took an exhaustive initial exam which included the measuring of the aerobic capacity through a specific laboratory test. After that, the sudden death cases were registered during the time tracking.
It was verified that the aerobic capacity level is inversely proportional to the risk of suffering a sudden cardiac death event. Those participants with moderated or high levels of aerobic capacity had between a 44 and 48% lower risk of suffering a sudden cardiac death event than those with low aerobic capacity. These results were higher when analysing the specific role of the aerobic capacity in people with obesity and hypertension, since it was proved that a moderated or high aerobic capacity could reduce between a 58 and 72% the risk of sudden cardiac death.
The main conclusion of this study suggests that the risk of sudden cardiac death in men and women could be partially reduced if the aerobic capacity achieve moderate to high levels. This improvements begin to produce progressively with small increments of the aerobic capacity (14% of decrease for each METs of increase - unit of measure to express the aerobic functional unity-). For all of that, it must be remarked that "it is necessary to encourage the population to entrust professional of physical activity and exercise to improve their physical fitness in a safe and progressive way," according to the researchers in charge of this study from the Physical, Plastic Arts and Music Education Department from the UCA where they carry out their research activity currently.

Story Source:
Materials provided by Universidad de CádizNote: Content may be edited for style and length.

Journal Reference:
  1. David Jiménez-Pavón, Enrique G. Artero, Duck-chul Lee, Vanesa España-Romero, Xuemei Sui, Russell R. Pate, Timothy S. Church, Luis A. Moreno, Carl J. Lavie, Steven N. Blair. Cardiorespiratory Fitness and Risk of Sudden Cardiac Death in Men and Women in the United States.Mayo Clinic Proceedings, 2016; 91 (7): 849 DOI:10.1016/j.mayocp.2016.04.025

Diet and exercise may improve physical function and quality of life in older obese adults

A recent review and analysis of published studies since 2005 found low-to-moderate evidence that dietary and exercise interventions can improve physical function and quality of life in older adults with obesity.
The analysis included six unique studies plus 13 that were based on the same study population, with a total of 405 adults with obesity all aged ≥60 years but whose average study group age was ≥65years.
The review's authors noted that well-designed, randomized controlled trials are needed to provide definitive guidance on how to address obesity in older individuals.
"Obesity in older adults is a significant public health concern that will increasingly become a burden to society if we do not address it promptly," said Dr. John Batsis, author of the Journal of the American Geriatrics Society study. "We need solid evidence on how to effectively engage this group of patients to not only improve their weight but, importantly, improve their physical function."

Story Source:
Materials provided by WileyNote: Content may be edited for style and length.

Journal Reference:
  1. John A. Batsis, Lydia E. Gill, Rebecca K. Masutani, Anna M. Adachi-Mejia, Heather B. Blunt, Pamela J. Bagley, Francisco Lopez-Jimenez, Stephen J. Bartels. Weight Loss Interventions in Older Adults with Obesity: A Systematic Review of Randomized Controlled Trials Since 2005.Journal of the American Geriatrics Society, 2016; DOI:10.1111/jgs.14514

Heavy hitters: Obesity rate soars among professional baseball players

Major League Baseball players have become overwhelmingly overweight and obese during the last quarter century, say health researchers.
David E. Conroy, Penn State professor of kinesiology, and colleagues looked at 145 years of data on professional baseball players' body mass. The researchers found that the athletes' weight held steady for over 100 years, with the majority of them weighing in at what is considered "normal," -- i.e., with a body mass index (BMI) between 18.5 and 24.9.
However, around 1991 the average player's BMI began to rise, and over the last 25 years nearly 80 percent of players fall into the overweight or obese category with a BMI above 25. Obesity in the general U.S. population began to rise in the mid-1970s, according to the Centers for Disease Control and Prevention.
"Research exists that shows how having extra weight can help with certain aspects of baseball," said Conroy, also professor of human development and family studies. "The more force a batter can put into the ball, the further it will travel."
The researchers used the publicly available Lahman Baseball Database, where players' height, weight and age are recorded for their debut year in Major League Baseball. The data were self-reported, however Conroy points to the trend of players' increasing weight as informative -- and cause for some concern.
Conroy and colleagues report their findings in Obesity Research and Clinical Practice.
"The data are observational, and raise more questions than they answer," cautioned Conroy. "BMI can be misleading, because it doesn't take body composition into account. What kind of pounds are the players adding? Are they mostly muscle or fat?"
The rise coincides with baseball's steroid era, and steroids are known to cause weight gain in some. But the rise also lines up with advances in sports science and nutrition, which have enabled athletes to better train and fuel, helping them build muscle and endurance -- which could lead to weight gain as well.
"These trends warrant further attention because of the potential for adverse long-term health consequences in this population and those who perceive them as role models for health and human performance," the researchers wrote.

Story Source:
Materials provided by Penn State University. Original written by Victoria M. Indivero. Note: Content may be edited for style and length.

Journal Reference:
  1. David E. Conroy, Kathleen Y. Wolin, Mercedes R. Carnethon.Overweight and obesity among Major League Baseball players: 1871–2015Obesity Research & Clinical Practice, 2016; 10 (5): 610 DOI: 10.1016/j.orcp.2016.09.003

Fungus in humans identified for first time as key factor in Crohn's disease

A Case Western Reserve University School of Medicine-led team of international researchers has for the first time identified a fungus as a key factor in the development of Crohn's disease. The researchers also linked a new bacterium to the previous bacteria associated with Crohn's. The groundbreaking findings, published on September 20th in mBio, could lead to potential new treatments and ultimately, cures for the debilitating inflammatory bowel disease, which causes severe abdominal pain, diarrhea, weight loss, and fatigue.
"We already know that bacteria, in addition to genetic and dietary factors, play a major role in causing Crohn's disease," said the study's senior and corresponding author, Mahmoud A Ghannoum, PhD, professor and director of the Center for Medical Mycology at Case Western Reserve and University Hospitals Cleveland Medical Center "Essentially, patients with Crohn's have abnormal immune responses to these bacteria, which inhabit the intestines of all people. While most researchers focus their investigations on these bacteria, few have examined the role of fungi, which are also present in everyone's intestines. Our study adds significant new information to understanding why some people develop Crohn's disease. Equally important, it can result in a new generation of treatments, including medications and probiotics, which hold the potential for making qualitative and quantitative differences in the lives of people suffering from Crohn's."
Both bacteria and fungi are microorganisms -- infinitesimal forms of life that can only be seen with a microscope. Fungi are eukaryotes: organism whose cells contain a nucleus; they are closer to humans than bacteria, which are prokaryotes: single-celled forms of life with no nucleus. Collectively, the fungal community that inhabits the human body is known as the mycobiome, while the bacteria are called the bacteriome. (Fungi and bacteria are present throughout the body; previously Ghannoum had found that people harbor between nine and 23 fungal species in their mouths.)
The researchers assessed the mycobiome and bacteriome of patients with Crohn's disease and their Crohn's-free first degree relatives in nine families in northern France and Belgium, and in Crohn's-free individuals from four families living in the same geographic area. Specifically, they analyzed fecal samples of 20 Crohn's and 28 Crohn's-free patients from nine families and of 21 Crohn's-free patients of four families. The researchers found strong fungal-bacterial interactions in those with Crohn's disease: two bacteria (Escherichia coli and Serratia marcescens) and one fungus (Candida tropicalis) moved in lock step. The presence of all three in the sick family members was significantly higher compared to their healthy relatives, suggesting that the bacteria and fungus interact in the intestines. Additionally, test-tube research by the Ghannoum-led team found that the three work together (with the E. coli cells fusing to the fungal cells and S. marcescens forming a bridge connecting the microbes) to produce a biofilm -- a thin, slimy layer of microorganisms found in the body that adheres to, among other sites, a portion of the intestines -- which can prompt inflammation that results in the symptoms of Crohn's disease.
This is first time any fungus has been linked to Crohn's in humans; previously it was only found in mice with the disease. The study is also the first to include S. marcescens in the Crohn's-linked bacteriome. Additionally, the researchers found that the presence of beneficial bacteria was significantly lower in the Crohn's patients, corroborating previous research findings.
"Among hundreds of bacterial and fungal species inhabiting the intestines, it is telling that the three we identified were so highly correlated in Crohn's patients," said Ghannoum. "Furthermore, we found strong similarities in what may be called the 'gut profiles' of the Crohn's-affected families, which were strikingly different from the Crohn's-free families. We have to be careful, though, and not solely attribute Crohn's disease to the bacterial and fungal makeups of our intestines. For example, we know that family members also share diet and environment to significant degrees. Further research is needed to be even more specific in identifying precipitators and contributors of Crohn's."

Story Source:
Materials provided by Case Western Reserve UniversityNote: Content may be edited for style and length.

Journal Reference:
  1. G. Hoarau, P. K. Mukherjee, C. Gower-Rousseau, C. Hager, J. Chandra, M. A. Retuerto, C. Neut, S. Vermeire, J. Clemente, J. F. Colombel, H. Fujioka, D. Poulain, B. Sendid and M. A. Ghannoum. Bacteriome and Mycobiome Interactions Underscore Microbial Dysbiosis in Familial Crohn’s DiseasemBio, September 2016 DOI:10.1128/mBio.01250-16

Now is the lightest you will weigh all year

As swimsuit season wanes and the holiday season edges closer, Americans everywhere should take a moment to enjoy the current state of their waistline. For the average person, the time just before the start of the holiday season is the low point in an annual weight gain pattern that peaks during the holidays and takes nearly half a year to fully shed.
New research findings published Sept. 27 in the New England Journal of Medicine by Cornell Food and Brand Lab Director Brian Wansink and colleagues from Tampere University of Technology of Finland analyze the wireless weigh-ins of nearly 3,000 individuals in three countries.
In the U.S., weight patterns begin rising at Thanksgiving and peak around Christmas and New Year's.
"We found that in the U.S., it isn't until after Easter, about a five-month period, that weight patterns even out," said Wansink, "Chances are, right now most Americans are at their lowest weight of the year."
The trend among the 1,781 American participants indicated a weight bump of 0.2 percent during Thanksgiving, and another 0.4 percent at Christmas. It takes about five months to lose those holiday pounds, with weights typically stabilizing from May to November before the cycle begins anew.
The study used scales that sent data over a Wi-Fi connection rather than requiring participants to self-report or visit a testing site for weigh-ins.
The researchers also analyzed yearly weight patterns of 760 German and 383 Japanese participants. Similar to their American counterparts, those in Germany weigh the most around Christmas, while those in Japan weigh the most during Golden Week, four major holidays in the spring. Each country also showed a peak in weight gain at New Year's.
"Everyone gains weight over the holidays -- Americans, Germans, Japanese," said Wansink.
But, he said, an annual holiday ritual repeated at the start of the season could go a long way.
"Instead of making a New Year's resolution, make an October resolution," Wansink said. "It's easier to avoid holiday pounds than to lose them after they happen."

Story Source:
Materials provided by Cornell University. Original written by Katie Baildon. Note: Content may be edited for style and length.

Journal Reference:
  1. Elina E. Helander, Brian Wansink, Angela Chieh. Weight Gain over the Holidays in Three CountriesNew England Journal of Medicine, 2016; 375 (12): 1200 DOI:10.1056/NEJMc1602012

Thursday, September 29, 2016

Milk intake is objectively not linked to increased cardiovascular risk, study suggests

Researchers in Valencia participated in an international study that has debunked the association between milk and dairy products and increased cardiovascular risk. Lecturer Óscar Coltell of the Universitat Jaume I de Castellón led the computational analysis of the masses of data obtained in relation to an innovative new biomarker.
The study, led by Dr. Dolores Corella at the Spanish Biomedical Research Networking Centre in Physiopathology of Obesity and Nutrition (CIBERobn), has identified a means of measuring patient intake of milk and dairy products that by-passes traditional reliance on questionnaire- and interview-based estimations. Specifically, the team has identified a new biomarker that can reliably indicate consumption in both Mediterreanean and American populations.
This biomarker lends a lens of objectivity to an issue that has divided opinion for some time now: the association between the consumption of milk and dairy products and cardiovascular risk. Studies so far have yielded contradictory results, which is perhaps not surprising since their main source of data is patient memory and recall. Nutritional biomarkers, also known as genetic proxies, provide objetive assessment of food intakes and are being used to counter this bias. Indeed, in nutritional research the hunt for new biomarkers targeting different foodstuffs is intensifying, Corella tells us.
Of particular interest are single nucleotide polymorphisms (SNPs). In this study, the researchers have identified one such polymorphism in the MCM6 gene (MCM6-rs3754686 SNP), already identified as a marker of lactose tolerance, with strong associations with the consumption of milk in the European Mediterranean population, and in the white, Afroamerican and Hispanic populations.
Interestingly, a diferent polymorphism (MCM6-rs4988235) had already been identified as a biomarker in research with Danish test subjects. However, although this biomarker works in northern European populations, the association with milk intake is not so strong in populations of other origins.
Corella tells us that her part of the study, carried out under the national PREDIMED project, was based on food intake data obtained yearly over five years from more than 7000 people. Blood samples were subject to broad spectrum genomic analysis. Combined with the data provided by the Human Nutrition Research Center on Aging in Boston, which also participated in the study, data was collected from a total of over 20,000 patients.
This is where Óscar Coltell, lecturer at the department of Computer Languages and Systems at Universitat Jaume I (UJI) came in: he led the meta-analysis of the masses of data obtained, designing computational methods for extracting meaningful information (anthropometric, biochemical, genetic and statistical analyses) and developing bioinformatic techniques to search for new identifying markers. Furthermore, the computational methods developed enable in-depth analysis by subgroups.
No association between milk intake and cardiovascular risk
Besides the contribution of a reliable genetic marker for the intake of dairy products, the study reports no significant association between a greater dairy intake and increased values for cardiovascular risk factors, including cholesterol, triglycerides and glucose, where previous studies have typically given contradictory results.
The study was published in Scientific Reports.

Story Source:
Materials provided by Asociación RUVIDNote: Content may be edited for style and length.

Journal Reference:
  1. Caren E. Smith, Oscar Coltell, Jose V. Sorlí, Ramón Estruch, Miguel Ángel Martínez-González, Jordi Salas-Salvadó, Montserrat Fitó, Fernando Arós, Hassan S. Dashti, Chao Q. Lai, Leticia Miró, Lluís Serra-Majem, Enrique Gómez-Gracia, Miquel Fiol, Emilio Ros, Stella Aslibekyan, Bertha Hidalgo, Marian L. Neuhouser, Chongzhi Di, Katherine L. Tucker, Donna K. Arnett, José M. Ordovás, Dolores Corella.Associations of the MCM6-rs3754686 proxy for milk intake in Mediterranean and American populations with cardiovascular biomarkers, disease and mortality: Mendelian randomizationScientific Reports, 2016; 6: 33188 DO

Is salt really scary for our health?

Weigh in on controversy for salt intake and heart disease ..
Salt makes our body hold on to water. If we eat too much salt, it will raise the blood pressure relatively due to the extra water stored in the body. So, the more salt we eat, the higher will be our blood pressure which in-turn will exert greater strain on our heart, brain, arteries, and kidneys.
There are many clinical and medical findings call into question the common wisdom that excess salt is bad for you, but the evidence linking salt to heart disease has always been tenuous.
And low-salt diets could have side effects: when salt intake is cut, the body responds by releasing renin and aldosterone, an enzyme and a hormone, respectively, that increase blood pressure. 

While it is evident that an excessive high sodium intake is linked to greater risk of cardiovascular disease and hypertension illness, a low sodium diet may also aleviate the risk for people with or without hypertension.

Based on WHO, the target to reduce salt intake to less than 5g/day remain valid as a health conscious guideline. However, if one have hypertension and heart disease or kidney problems, then one should absolutely abstain from a high salt intake. 

There is more to managing a healthy heart than simply limiting salt intake. Ultimately, it's about maintaining a balanced diet, regular exercise, and leading an active lifestyle in keeping the heart pumping in healthy mode.

So it is in fact the RIght Amount in relation to the "pinch of salt" 

Exercise Costs: Staying Fit Can Cut Your Medical Bills

Staying fit not only adds years to your life, but also plenty of dollars to your wallet, finds a new study published Wednesday in the Journal of the American Heart Association.
Researchers pored through data from an earlier nationally representative survey of some 26,000 Americans over the age of 18. After accounting for people who were unable to exercise regularly, pregnant, or underweight, they found a consistent pattern: People who said they met the recommended criteria for moderate to vigorous exercise on a weekly basis on average paid less in medical expenses annually than those who didn’t. The largest savings could be seen with people who had a history of cardiovascular disease — they paid around $2,500 less in medical costs compared to their counterparts who worked out less.  
“Even among an established high-risk group such as those diagnosed with heart disease or stroke, those who engaged in regular exercise activities reported a much lower risk of being hospitalized, (having) an emergency room visit and use of prescription medications,” said study senior author Dr. Khurram Nasir, director of the Center for Healthcare Advancement & Outcomes and the High Risk Cardiovascular Disease Clinic at Baptist Health South Florida, in a statement.
Person with running shoesA new study finds that exercising three to five times a week may save you loads of money in annual medical costs, especially if you have a history of cardiovascular disease.Pixabay, Public Domain
Exercisers who were already in relatively good health with no preexisting chronic conditions also received a discount. They spent around $500 less annually compared to similar non-exercisers. Though they had lower savings, these healthier individuals spent less on medical costs to begin with compared to heart and stroke patients. Approximately one-half of the former group reported regular exercise vs one-third of cardiovascular disease patients.  
Collectively, the researchers estimated that if just 20 percent of currently loafing cardiovascular disease patients began exercising regularly, the country would save billions of dollars annually in medical costs. Regular exercise is defined as 30 minutes of moderate-intensity aerobic activity 5 days a week, or at least 25 minutes of vigorous aerobic activity 3 days a week, according to the American Heart Association
For all the hopes of miraculous life-extending medical treatments, it seems that a brisk jog or walk three to five times a week is essential to creating a well-lived life.  
“The message to the patient is clear: There is no better pill in reducing the risk of disease and healthcare costs than optimizing physical activity,” Nasir said.
Source: Nasir K, et al. Journal of the American Heart Association. 2016.

Wednesday, September 28, 2016

The New Weight-Loss Math

You may have noticed that calorie counts are everywhere: Stamped on packaged foods, plastered on restaurant menu boards and found alongside cookbook recipes. And if you’re a health-conscious eater, chances are you pay a great deal of attention to these numbers in the name of cleaner, calorie-controlled eating. / But what may shock you is that research shows calorie counting when it comes to dieting is at best overrated and at worst highly misleading. 
You see, calorie stats are based on a century-old formula called the Atwater system, in which the macronutrient components — carbohydrate, fat and protein — of a food have a set number of calories (a unit of energy). Carbohydrates and protein have four calories in each gram and fat contains a more lofty nine calories. So if a food has 8 grams of fat, 3 grams of protein and 7 grams of carbohydrate, theoretically it should deliver 112 calories to whoever eats it. But this fails to tell the whole picture when it comes to the calories your body actually extract from foods. Why? Because not all calories are created equal. 
The number of calories listed on a food label or fitness app can be very different from what you end up absorbing. That’s because the net amount of calories you obtain from your meals and snacks is heavily influenced by a number of factors. It turns out instead of counting calories you need to focus on eating more of the right kinds of foods so fewer calories are absorbed and you have a better chance of being leaner. That’s why it’s vital to take a look at the most recent research when it comes to calories and learn how to hack the science to keep you on track for physique greatness.

Protein Power

There is one very good reason why diets higher in protein have been shown to make it easier for you to hold onto your abs: Protein-rich foods make your metabolism burn hottest.
A big shortfall of the Atwater system for estimating the calories in food is that it fails to take into account the thermic effect of feeding. Think of TEF as the energy cost of chewing, digesting, absorbing, transporting and storing the food you eat. It turns out that protein has a significantly higher TEF than carbohydrates and fat. The TEF of protein ranges from 20 to 35 percent, whereas it costs us only about five to 10 percent of the energy consumed from carbohydrates or fats to digest and process them. In a study of people on a high-calorie diet, those who got 25 percent of calories from protein burned 227 more a day (and packed on more muscle) than those who only ate five percent of calories from protein. 
In other words, researchers at Tufts University determined that over a period of 16 to 24 years those who ate more protein at the expense of carbohydrates tended to pack on less weight. Protein contains nitrogen, which must be stripped off and eliminated by the liver and this extra metabolic step as well as other differences between the macronutrients is why the body requires more energy to handle protein. So even though carbs and protein have the same calories per gram (four calories in a gram), you net fewer of them from the latter.
Take Action: Owing to the abundance of protein, the true calorie count of a chicken breast, slab of beef or a bowl of Greek yogurt is likely lower than as advertised on the label. For this reason, you want to make sure that each of your meals and snacks includes plenty of protein at the expense of some carb and fat calories to reap the rewards of this calorie-burning (and muscle-making!) advantage. And continue to blitz whey protein, which has a particularly high TEF according to a 2011 American Journal of Clinical Nutrition study, into your postworkout shakes. Besides, protein is satiating, so you’ll be satisfied on less. Glazed doughnut? Not so much!

Go Nuts

Modern research shows that when it comes to eating with the purpose of zapping ab flab, you would be well served to eat closer to Mother Nature to benefit from some notable calorie savings, and there’s no better place to start than with whole nuts. A study published in the American Journal of Clinical Nutrition determined that a one-ounce serving of almonds provides the human body with about 129 calories, which is about 22 percent fewer than the 167 calories determined by the Atwater system and what is currently shown on nutrition labels. A similar study conducted on pistachios and published in the British Journal of Nutrition found that nuts may contain up to six percent fewer calories than previously measured. And walnuts have been found to deliver 21 percent less energy to the body than once thought.
Strong cell membranes of plant foods like nuts may lock in some of their macronutrients, including fat, thereby preventing them and the energy they provide from being fully absorbed through the digestive tract. So although a handful of walnuts may contain 15 grams of fat, which translates into 135 calories, it’s likely not all of these fat calories are being absorbed. These fascinating results could help explain the results from studies showing that nut eaters are less likely develop a round belly. On the flipside, we may absorb more calories from a food when its cell walls have been broken down through processing. So peanut butter could very well provide more digestible calories than do whole peanuts.
Take Action: As with whole nuts, we may also absorb fewer calories from other foods like legumes, seeds, whole grains and vegetables consumed in their least processed states. Processing such as juicing fruits and milling grains ruptures cell walls and in the process reducing the energy needed for digestion. So to help in the battle of the bulge, more often try eating almonds instead of almond butter, apples instead of applesauce, wheat berries instead of whole-wheat spaghetti or whole-wheat flour, oranges instead of orange juice and cacao nibs instead of chocolate bars. Grinding meat into hamburger also may increase calorie absorption by making things easier for your digestive system, so consider steaks over burgers for a protein fix.

Reign of Whole Grain

One of the most prevalent weight-loss myths is that all calories are essentially the same. Take in too many of any calories and you’ll punch your ticket to pudgeville. But we now know that some calories work harder to keep your physique in tip-top shape. Case in point: A study in the journal Food & Nutrition Research provided volunteers either a sandwich made with multigrain bread and cheddar cheese or one made with highly processed white bread and cheese slices. Even though both meals had the same amount of total calories on paper, the less-processed sandwich meal required nearly twice as much energy to digest resulting in fewer calories being available to the body for storage. The processed sandwich used only 11 percent of the food’s calories for the needs of digestion, but the multigrain sandwich used almost 20 percent. So calorie counters take note: This is a good example of how nutrition trumps numbers tallying when it comes to winning the battle of the bulge.
Take Action: Again, this is proof that it’s harder for your digestive system to break down foods that are closer to their natural state, which can translate into calorie savings and making it easier for you to knock a few inches off your waistline. In other words, give your digestive system a bigger workout by shunning processed items like white rice for their more natural counterparts like brown rice. Not to mention eating more fiber-rich whole foods like vegetables, beans and whole grains will keep you feeling full and satisfied, most likely reducing your total calorie consumption while simultaneously increasing the nutrient density of your diet.

Bug Love

When you bite into your lunch sandwich you aren’t the only one feasting on it. Our guts are teeming with trillions of bacteria that also rely on this nourishment. And emerging research suggests various types of bacteria in your digestive tract help your body absorb calories from food. That means if there is a robust population of the type of bacteria that breaks down food into energy, you may be soaking up more calories from the food you eat. So the makeup of your microbiome could play a vital role in the overall calorie cost of your diet and, in turn, weight management by making you more or less prone to absorbing and storing extra calories.
Take Action: Consider splurging for organic meats and dairy more often. It looks like the millions of pounds of antibiotics used in conventional livestock production each year can skew the population of bugs in your gut, nurturing those that are more efficient at pulling calories from food and transporting them into your system. Beyond eating antibiotic-free steak and milk and not taking antibiotics for every cough you have, load up on high-fiber vegetables, fruits and whole grains since fiber can help foster a population of microbes that are less efficient at extracting energy from food. And in terms of your waistline, that is a good thing.

Raw Power

It’s not necessary for you to completely eschew your oven when trying to shed some weight, but it might be a good idea to nosh on raw foods more often.
A watershed study by Harvard scientists in the Proceedings of the National Academy of Sciences showed that cooking actually increases the amount of calories our bodies absorb from food. The study authors believe that cooking performs some of the digestive process for us such as denaturing proteins and gelatinizing starches, meaning that our bodies don’t expend as much energy dealing with digestion and thereby allowing more calories to be available. Further, larger quantities of raw food require more laborious chewing, which expends additional energy and also encourages satiety. So the total amount of calories we glean from raw carrots or raw fish (yum, sushi!) could very well be less than from the same portion of roasted carrots or fish sticks. And a medium-rare steak could very well deliver less energy to the body than a well-done piece of beef since its muscle fibers might be more tightly wound as a result of a shorter cooking time and, in turn, requiring extra work for your digestive system to untangle.
Take Action: Back in the day, putting meat to fire allowed our ancestors to obtain more energy to develop bigger brains, but now eating too many cooked processed foods are giving modern humans bigger guts. After all, punching computer keys all day requires less energy than that required to take down woolly mammoths. So tap into the fat-frying power of raw foods by working them into your daily menu. This can be accomplished by tossing a handful of raw sunflower seeds or nuts into breakfast oatmeal, snacking on raw baby carrots or raw fruits like pears, serving a raw salad at every dinner meal and even experimenting with recipes for ceviche, a raw seafood dish. Cooking root vegetables increases their levels of absorbable carbohydrates from the intestines, so why not try working shredded raw beets or turnips into salads instead of sending them to the fire. And if you eat pasta, enjoy it al dente to give your digestive tract more of a workout.

Rock Solid

When it comes to the calories you consume each and every day, form matters. A study in the journal Obesity exposed people to the same number of calories in liquid or solid form only to find that post-meal hunger and desire to eat were greater when subjects consumed liquid calories. It appears that a solid meal leads to a greater drop in levels of the hunger-inducing hormone ghrelin, which could help tame your appetite. Similarly, the fibrous structure in whole fruit helps slow the absorption of its naturally occurring sugars, which can contribute to satiety. The takeaway is that the body doesn’t register 300 liquid calories in the same way it does if those 300 calories came in the form of whole food which could lead to increased hunger and higher overall daily calorie intake. Hence, one reason for the strong association between soda intake and weight gain.
Take Action: While your postworkout protein shake won’t derail your diet, be careful not to become too chummy with your blender. Overall, you want most of your daily calories to come in the form of solid food. (Beverage intake accounts for up to 20 percent of calories in the typical American diet.) That means bidding adieu to orange juice in favor of a whole orange, opting for a kale salad instead of green juice and saying sayonara to sweetened drinks like soda for calorie-free options like water or tea. And when you do whip up smoothies, make them so they stick to a spoon. A Dutch study discovered that a thick milkshake lead to greater feelings of fullness than a thinner version despite containing only one-fifth of the calories. For this reason, a bowl of yogurt is likely to quell your hunger more than a glass of milk.

Watch the Clock

When you consume your calories might matter as much as how many you take in. When Italian researchers looked at the eating habits of more than 1,200 adults they discovered that the risk of being obese was greatly increased for study participants who consumed half or more of their daily calories at dinner. Along the same lines, a study in the journal Obesity discovered that volunteers who consumed more calories at breakfast at the expense of calories later in the day (700 calories at breakfast, 500 at lunch, 200 at dinner) experienced greater fat loss around their waistlines than those who took in substantially more calories at dinner than breakfast (200 calories at breakfast, 500 at lunch, 700 at dinner). And Spanish scientists showed that when people ate lunch after 4:30 p.m., they burned fewer calories while resting and digesting their food than they did when they took in their meal at 1 p.m. — even though the calories eaten and level of activity was the same.
It could be that we burn more calories earlier in the day when our metabolisms are higher, while later noshes are more likely to go into fat storage. Insulin sensitivity may also fall as the day progress, so there is a greater chance that the carbohydrates consumed will get stocked away in fat stores. What all this means is that when it comes to fending off the flab monster a calorie consumed at daybreak may not be the same as a calorie eaten after sunset. Late-night calories are more prone to be stored as body fat.
Take Action: This research shows it might be a good idea to follow this sage advice: “Eat breakfast like a king, lunch like a prince and dinner like a pauper.” If you are struggling to keep your beach body, consider making your morning repast more substantial and then tapering down calorie intake as the day progresses. Besides, a substantial breakfast can also work to promote satiety early in the day and lessen the risk for mindless snacking later in the day

The spice of life: Cinnamon cools your stomach

Adding cinnamon to your diet can cool your body by up to two degrees, according to research published today.
And the spice may also contribute to a general improvement in overall health.
The research has been published in the journal, Scientific Reports.
Project leader Distinguished Professor Kourosh Kalantar-zadeh, from RMIT's School of Engineering, said the results of the study, which used pigs, seemed to show that cinnamon maintained the integrity of the stomach wall.
"When pigs feed at room temperature, carbon dioxide (CO2) gas increases in their stomach.
"Cinnamon in their food reduces this gas by decreasing the secretion of gastric acid and pepsin from the stomach walls, which in turn cools the pigs' stomachs during digestion.
"When the pigs are hot, they hyperventilate, which reduces CO2production. With cinnamon treatment, CO2 decreases even further.
"This not only cools the pigs but leads to a significant improvement in their overall health."
Fellow researcher Dr Jian Zhen Ou said: "Altogether cinnamon cooled the stomach by up to 2C.
"No wonder cinnamon is so popular in warm regions as taking it makes people feel better and gives them a feeling of cooling down."
The research is part of a bigger study at RMIT into gut health using swallowable gas sensor capsules or smart pills, developed at the University.
Kalantar-zadeh said gut gases were the by-product of digestion and could provide valuable insights into the functioning and health of the gut.
"Our experiments with pigs and cinnamon show how swallowable gas sensor capsules can help provide new physiological information that will improve our understanding of diet or medicine.
"They are a highly reliable device for monitoring and diagnosing gastrointestinal disorders. They will revolutionise food science as we know it."
Scientists at the University of Melbourne and Monash University also contributed to the paper, entitled "Potential of in vivo real-time gastric gas profiling: a pilot evaluation of heat-stress and modulating dietary cinnamon effect in an animal model."

Story Source:
Materials provided by RMIT UniversityNote: Content may be edited for style and length.

Journal Reference:
  1. Jian Zhen Ou, Jeremy J. Cottrell, Nam Ha, Naresh Pillai, Chu K. Yao, Kyle J. Berean, Stephanie A. Ward, Danilla Grando, Jane G. Muir, Christopher J. Harrison, Udani Wijesiriwardana, Frank R. Dunshea, Peter R. Gibson, Kourosh Kalantar-zadeh. Potential of in vivo real-time gastric gas profiling: a pilot evaluation of heat-stress and modulating dietary cinnamon effect in an animal modelScientific Reports, 2016; 6: 33387 DOI: 10.1038/srep33387