Monday, January 28, 2013

Reishi: the Mushroom of Kings


Being a member of the Research and Development and Product Development teams for Designs for Health affords me the opportunity to perform scientific literature searches and investigations into the clinical and therapeutic properties of many different botanically-derived compounds and substances. Personally, I’m of the opinion that most, if not all, the answers to our healthcare needs lie in the natural world. We have simply to discover them.

One class of medicinally oriented botanicals I find incredibly interesting is the medicinal mushrooms. While mostly famous and ubiquitous in Japanese and Chinese healing traditions, the power of these mushrooms is being studied in western medicine for a vast number of therapeutic properties.

reishi mushroomPossibly the most well known of the medicinal mushrooms is thereishi – Ganoderma lucidum or Ling Zhi as it is known in China). Ling Zhi translates to “divine plant of longevity” but is also known as the “mushroom of immortality” and “the mushroom of kings.” As reishi has been used in China for over 2,000 years, the name brings to mind Chinese emperors, ancient mountainous forests, and dark, dank and dusty old herbal apothecaries run by wizened herbal wizards.

In the wild, reishi grow on hardwoods such as maple, oaks, and elms but are now very rare and difficult to find in their natural habitat. Therefore, most reishi sold today is cultivated commercially.

Immunoprotective properties

This hard, woody, bitter and subsequently inedible mushroom contains multiple active ingredients including polysaccharides and triterpenes which are currently primarily being studied for their immune system-enhancing and possible cancer-fighting effects.

Specific polysaccharides, known as href="http://catalog.designsforhealth.com/ImmunoBerry-Liquid?sc=2&category=3780">beta-glucans, are thought to stimulate the immune system to fight cancer by what researchers believe to be a variety of mechanisms of action including stimulating the production of T cells, NK cells and macrophages to fight the afflicted cells, inhibiting the adhesion of cancerous cells to normally functioning endothelial cells.

Men’s health

The triterpines found in Ganoderma lucidum extracts also inhibit the 5 alpha-reductase enzyme, which converts testosterone to dihydrotestosterone and is upregulated in benign prostatic hyperplasia (BPH). This makes it a possible therapeutic tool for men to help fight against BPH, lower urinary tract symptoms, and possibly prostate cancer.

Liver support

Reishi has been shown to be liver protective, reducing fibrosis and associated liver damage in toxin induced hepatopathologies.

reishi mushroomsNeuroprotective properties

Additionally, reishi extracts have demonstrated neuroprotective properties through its modulation of inflammatory cytokines. For instance, in cell studies, reishi was shown toprotect dopaminergic neurons whose damage is implicated in the pathogenesis of Parkinson’s disease.

Autoimmune support

Reishi has shown efficacy in models of autoimmunity. For example, it was shown todecrease the symptoms associated with Sjogren’s syndrome, a condition where the body’s lymphocytes attack salivary glands and which is very difficult to treat. Reishi may also prove to be useful in rheumatoid arthritis, another autoimmune condition, as it demonstrated analgesic characteristics in patients suffering with this condition.

Protection during cancer therapies

There are many, many studies showing reishi’s potential as an adjunctive therapeutic tool but it’s also been shown to protect normal cells from the ravages of both radiation and chemotherapies, making it a strong consideration as a complement to traditional cancer therapies

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