Higher levels of the omega-6 polyunsaturated fatty acid (PUFA) linoleic acid stored in fat tissue was associated with a lower risk of death in a Swedish prospective cohort study which followed older men for 15 years.
Linoleic acid stored in adipose tissue was associated with a 10% lower risk for all-cause mortality (P=0.02) and a trend toward lower cardiovascular mortality in the Uppsala Longitudinal Study of Adult Men (ULSAM), reported researcher David Iggman, MD, PhD, of Sweden’s Uppsala University, and colleagues, in the journal JAMA Cardiology.
The study is the largest ever to examine dietary levels of specific fatty acids in adipose tissue as a marker of dietary intake, and to examine the impact of PUFA consumption on death and cardiovascular disease using this objective marker.
Its findings suggest a beneficial role of omega-6-rich vegetable oils — including corn, sunflower, canola, and soybean oil — on mortality and possibly cardiovascular health, the researchers wrote.
Many health groups, including the American Heart Association, consider consumption of polyunsaturated fats to be beneficial for heart health when used as a replacement for saturated and trans fats in the diet, but this dietary advice has been questioned in recent years.
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